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Ferroptosis: a new insight for treatment of acute kidney injury
H 2 O 2 produced during the oxidative folding of endoplasmic reticulum proteins has been found to regulate the signal transduction process of nuclear factor E2-related factor 2 (Nrf2), which in turn regulates the expression of downstream glutathione peroxidase 8 (GPX8), which in turn can participate in ER calcium regulation through endoplasmic reticulum calcium ATPase (SERCA) (Figure 7)
Primary deficiencies and deficiencies secondary to genetic diseases
"Chemotherapy for the treatment of malignant peripheral nerve sheath tumors in neurofibromatosis 1: a 10-year institutional review"
10.1038/s41366-024-01500-y 9 BuckeridgeC.CobainS.BaysH
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