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This expanded approval is based on results from the pivotal FLOW phase 3b clinical trial, which demonstrated that once-weekly semaglutide led to a statistically significant 24% reduction in the risk of kidney disease progression, kidney failure, and cardiovascular death compared to placebo, when added to standard care
Weight loss of 7-10% of body weight remains the most evidence-based intervention for improving liver health in NAFLD, as emphasised in NICE guidance
A missing FDA listing does not prove that a product is safe, effective, legal for personal use, or made to drug-quality standards
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