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To combat stigma, its incumbent on doctors to understand and raise awareness of the relevance of social and environmental determinants of childhood obesity, the guidelines say
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2021;320(3):C37591
7,9 The emergence and expansion of resistant clones are often driven by Darwinian evolutionary principles, whereby treatment selectively eliminates sensitive populations while allowing drug-tolerant persister (DTP) cells or preexisting resistant subclones to dominate
However, further retrospective case series have identified liver injury and hepatotoxicity in children following paracetamol intoxication, particularly following multiple sequential overdoses , and that the mortality in these cases can be high
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