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Rare but Serious Side Effects While the majority of side effects are manageable, there are rare instances where medical attention is necessary
It should be noted that the cerebral cortex and the cerebellum interestingly lack the expression of the GLP-1R in rat models [51]
We compared a 6 and 12-month change in total body weight loss (TBWL) for those receiving monotherapy from the initiation of GLP-1 analogue therapy with those receiving combination therapy from the initiation of bupropion/naltrexone added-on therapy
Side Effects Common Headache Nausea, vomiting Abdominal pain Constipation or diarrhea Bloating / flatulence Long-Term or Serious Vitamin B12 deficiency Hypomagnesemia Increased risk of fractures (hip, spine, wrist) Kidney injury (interstitial nephritis) C
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