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This is due to regulatory bodies like the FDA withholding their authorization for gabapentin utilization in this capacity

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While this models speaks to the peripheral effect of prkcg manipulation in the area of spinal cord Lamina II, a prkcg-dense area responsible for receiving sensory-related stimuli, including noxious, non-noxious stimuli, and regulation of pain sensations (Merighi, 2018), it is still unclear whether prkcg downregulation by ketamine plays a role in its central effects, although the potential for this effect exists in theory

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