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FOXO4-DRI at 25 mM concentration selectively induced p53 nuclear exclusion and apoptosis in the senescent Leydig cells, confirmed by Annexin V-FITC/PI apoptosis assays and immunofluorescent staining of Ser15-phospho-p53 foci
Junemani is a highly experienced GP with over 20 years of experience in the medical field
It is an important concept in pharmacology because it helps determine how long a compound remains active and how frequently it may need to be administered
Curr Protein Pept Sci (2019) 20:90717
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