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The washout period represents a brief cessation, and while 25 to 30 days is not long enough for full weight regain, it is enough for 2 to 5 pounds of regain in most people

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Cumulative incidence estimates are based on time from randomization to first EAC-confirmed cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke with non-CV death modeled as competing risk using the Aalen-Johansen estimator

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Severe and potentially life-threatening reactions like pancreatitis, bowel obstruction or infection of the gallbladder are also possible, although less common

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This dual action means it can: Control appetite even better than single-hormone medications Improve blood sugar control more effectively Lead to greater weight loss in many people Help your body use insulin more efficiently Tirzepatide is sold under the brand names Mounjaro for diabetes and Zepbound for weight loss

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Enlarged data points show the overall mean body-weight loss versus overall responder rate

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