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A study on the protective mechanism of liraglutide on cortical neurons after ischemia suggested that liraglutide probably reversed the ischemia-induced apoptosis by activating the PI3K/AKT and MAPK pathways (87)

Additionally, if appetite suppression is no longer noticeablesuch as returning interest in food or less sustained satiety after mealsyour clinician may recommend increasing to the next dose level to maintain the therapeutic effect

Then, 100 L of TMB solution and 100 L of H 2 O 2 (10 mM) in dimethyl sulfoxide (2 mM) were added to the NP solutions

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All experiments were performed following animal protocol approved by the Bar-Ilan University ethics committee (ethics approval number BIU-BIU-IL-2203-131-1)