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In HFD-fed Atg7 cKO mice and Parkin KO mouse models, some investigators found that deletion of Atg7 and Parkin inhibited mitophagy increased lipid accumulation, and exacerbated diastolic dysfunction, whereas injection of Tat-Beclin1 (TB1) increased mitophagy and attenuated cardiac dysfunction [174]
The potential for GLP-1 agonists to treat disorders like type-2 diabetes (T2D) was not lost on the endocrinology community (Reviewed here)
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The roGFP fluorescence was collected with a 505530 nm emission band-pass filter
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