135,136 It is considered a significant breakthrough in diabetes treatment and is also being studied for the treatment of obesity due to its significant weight loss effects
Le dosage exact dpend de l'tat de sant, de la rponse au traitement, de l'ge et du poids
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SGLT2 brain expression is lower compared to SGLT1, and it is localized mainly in the microvessels of the blood-brain barrier, in the amygdala, hypothalamus, periaqueductal gray, and in the dorsomedial medulla (Koepsell, 2020)
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