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That is normal in obesity and diabetes treatment, and it is one reason dose titration and medical review matter
Also, keep in mind that many pre-workouts, like Project-1, have other ingredients on top of citrulline malate to maximize blood flow
GLP-1RAs can increase microvascular perfusion in skeletal muscle through various pathways (175-178)
1a) and in the platypus GIP peptide (Supplementary Fig
But post-workout protein consumption, specifically within the 30 to 60 minutes after training, is critical for muscle protein synthesis
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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