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However, more human studies are needed to confirm these findings (7)
Putrescine serves as an immediate precursor for the other two polyamines spermidine and spermine synthesis through receiving the aminopropyl from decarboxylated S-adenosylmethionine (dcAdoMet or decSAM) by spermidine synthase (SPDSY) and spermine synthase (SPMSY), successively (Figure 1)
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