semaglutide cardiac ameliorates pressure overload-induced hypertrophy by improving cardiac mitophagy to suppress the activation of NLRP3 inflammasome Anti-inflammatory benefits of semaglutide: State

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Abstract Glucagon-like peptide-1 (GLP-1) is a 30-amino acid hormone secreted by L cells in the distal ileum, colon, and pancreatic cells, which participates in blood sugar regulation by promoting insulin release, reducing glucagon levels, delaying gastric emptying, increasing satiety, and reducing appetite

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Since 2022, the American Diabetes Association has updated its Standards of Care to recommend GLP1 receptor agonists as a firstline therapy for T2D 2 , eroding older and cheaper generics like metformin, which marks a momentous and fundamental change in treatment