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Weight loss is not solely dependent on willpower, as there are biological factors that affect metabolism, hunger, and weight that are beyond your control
Vta ( Principle of movement): Vata governs movement, sensory input, and nervous system activity
By contrast, when the NADH/NAD + ratio is low and mitochondria are depolarised, for example in the presence of a mitochondrial uncoupler, the enzyme switches to the reverse mode and oxidises mitochondrial NADPH to produce NADH
The biological rationale is interesting but unproven
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