These results are consistent with a study finding lower cerebrospinal fluid (CSF) levels of DSIP in hospitalized patients with schizophrenia or depressive disorders [13]
Pickart, L., Vasquez-Soltero, J., & Margolina, A
A better understanding of the complex physiology of weight regulation and the role of intestinal hormones in regulating food intake, appetite, and glucose homeostasis led to the discovery of GLP- 1 receptor analogs as safe and effective treatments, initially for T2DM and more recently in higher doses to treat obesity (liraglutide 3 mg and semaglutide 2.4 mg)
In the present study, disrupted hepatic glutathione homeostasis was observed in mice chronically exposed to a HFD diet, which is characterized by GSH reduction and GSSG elevation
10.1021/acs.chemrev.7b00258 16 FergusonG