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The small but significant increase in people with low blood pressure and with kidney stones are likely attributable to the fact that a combination of diarrhoea and reduced oral intake can lead some people to become somewhat fluid-depleted
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Scientific References Retatrutide, a GIP, GLP-1, and Glucagon Receptor Agonist, for Obesity (Jastreboff et al.)
Clinical takeaway: When the pattern doesn't fit classic OA, an early rheumatology evaluation changes outcomes
Each dose increase tends to restore some degree of appetite suppression and metabolic benefit
doi:10.1007/s11738-011-0801-1
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