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It also stimulates fibroblast proliferation, increases collagen I/II synthesis, enhances TGF-mediated ECM remodeling, and regulates MMPs to maintain balanced collagen turnover and promote orderly wound closure and tissue maturation (Wei et al
Targeting mitochondrial dynamics and metabolic flux regulation offers a novel strategy to disrupt cancer cell metabolic plasticity and enhance therapeutic efficacy [46]
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Acknowledgments We thank the patient for permitting us to use his data to complete this article
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