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or 13.3 kg), compared to 2.0% (4.6 lb

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Along with the possible paracrine effect of intestinal GLP-1, it is assumed that the effect of GLP-1 on food intake is controlled by two separate groups of vagal afferents, although the central mechanisms processing anorexic vagal nerve signals have not been fully studied [9]

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It has been hypothesized that GLP-1 RA effects may be adaptive, and improved IS may contribute to enhanced muscle function

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