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There can be large inter-individual variability in the extent of first-pass metabolism, leading to unpredictable plasma concentrations and responses after oral administration
This allows direct local exposure to intestinal tissues
Domestic refrigerators may not maintain consistent temperatures and are not equivalent to pharmaceutical cold storage
W., Lee, H
Niacin The niacin (vitamin B 3 ) coenzymes, NAD and NADP, are needed for several redox and other reactions in the body (see the article on Niacin)
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