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The SURPASS clinical trials have highlighted its significant A1C lowering and weight loss benefits, marking it as a promising option for patients with diabetes and obesity It is important to note that tirzepatide comes with a boxed warning for the risk of thyroid C-cell tumors, and it may delay gastric emptying, which could affect the oral absorption of other medications
glucagon receptor activation may elevate heart rate, and class-level risks include pancreatitis, gallbladder disease, and thyroid C-cell tumours based on animal data
It also supports more intensive weight loss goals based on the efficacy of and access to newer medications [5, 6]
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