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Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus
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Correspondingly, fat mass loss comprised a larger proportion of total weight loss among those who received apitegromab (85.3% of total loss (81.289.5%) or 8.5 kg (7.49.6)) compared to those who received placebo (69.5% (65.773.3%) or 8.0 kg (7.09.0))
It means there is often little benefit in increasing the dose if youre already losing weight steadily, your appetite remains well controlled, and youre feeling well
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