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This is precisely why prescription GLP-1 medications are engineered differently

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17: 2106 Weber EA, Knight A

However, with the growing evidence supporting use of particular agents in people with type 2 diabetes with specific profiles (comorbidities, overweight/obesity) and with the availability of multiple glucose-lowering agents with good efficacy and acceptable side effect profiles, the initiation of insulin can be postponed in many to later stages of the disease

Journal of the American Society for Mass Spectrometry