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De Miguel M, Yamamoto N, Raimbourg J, Cho BC, Gottfried M, Stemmer SM, et al

Drop back to the previous dose and attempt escalation again after an additional 2-4 weeks

In patients with Wilson's disease the breakdown and excretion of copper does not function properly so copper is deposited in various places in the body, such as the liver, brain, kidneys, and corneas

The combination means that while BPC-157 ensures the damaged area has adequate blood vessel growth (supply side), TB-500 ensures the cells migrating into the wound site have proper cytoskeletal regulation for effective repair (cellular side)

Report full dose-response relationships Two-dose designs are common and provide limited information