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Acknowledgements SRS and SSD are supported by funding from Michael Smith Health Research BC
The mechanisms behind the renoprotective effects of GLP-1 RAs involve anti-albuminuric, anti-inflammatory, natriuresis, anti-atherogenic, and anti-oxidant effects through protein kinase A signaling, induction of natriuresis by inhibiting sodium-hydrogen exchanger 3, and a reduction in hyperfiltration 27,30,31
Peptide regulation varies by jurisdiction and is evolving rapidly
10.1021/acschemneuro.0c00427 249
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