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Activation of Nrf2 by lithospermic acid ameliorates myocardial ischemia and reperfusion injury by promoting phosphorylation of AMP-activated protein kinase (AMPK)

It may also be used in people with a BMI of 27 or higher who have other weight-related medical conditions, such as type 2 diabetes or high blood pressure

The future of antioxidant therapy in DM lies in overcoming the limitations of broad-spectrum approaches by developing targeted, personalized, and mechanism-based interventions that address the nuanced role of OS in disease progression

There were few events of genital infection and increased urination in PIONEER 4 and 7, and no indication that the risk in patients treated with an SGLT2i was aggravated by concurrent treatment with oral semaglutide (see Table S4 in the Supplementary Information)

This review highlights the emerging roles of marine-sourced Sirtuin 1 (SIRT1) and Nuclear Factor Erythroid 2Related Factor 2 (NRF2) activators in modulating glucose and lipid metabolism, enhancing antioxidant defense mechanisms, and ameliorating cellular senescence