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34 It's advisable to increase fiber intake gradually over several weeks, along with adequate fluid intake, to allow the digestive system to adapt and minimize potential side effects like gas or bloating
Nonspecific mucocutaneous lesions The key difference between these nonspecific skin manifestations in lupus compared to the lupus specific manifestations, is that they appear not only in JSLE, but also in other inflammatory diseases
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doi:10.1126/scitranslmed.add1531 [52] Hulme H, Meikle LM, Strittmatter N, et al
The microbiota toxic substances lead to macrophage activation in the Kupffer cells, the livers resident macrophages, become activated by LPS and other microbial products, producing ROS and pro-inflammatory cytokines
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