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They can be functionalized with targeting ligands, such as antibodies or peptides, to selectively target specific tissues or cells for improved drug delivery
In vivo studies have also shown that injecting gp120 into the caudate-putamen of rats induces oxidative stress and BBB leakiness, with elevated MMP-2 and MMP-9 [191]
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Induction of phenylalanine ammonia-lyase and lipoxygenase in cotton seedlings by mechanical wounding and aphid infestation
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