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In a recent double-blind, randomized, placebo-controlled trial in women with abnormal mammograms, two-to-eight week consumption of about 250 mg/day of broccoli seed extract (~220 mg of glucoraphanin/day) before surgery failed to affect the expression of markers of proliferation and gene expression, including ki-67, p21, HDACs, and acetylated histones, in breast tissues collected after surgery (62)
The autophagic tumor stroma model of cancer
Andrikopoulos P, Aron-Wisnewsky J, Chakaroun R, et al
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On top of this, an enzyme called carnitine palmitoyltransferase-1 (CPT-1) is freed from additional inhibition, potentially shuttling more fatty acids into mitochondria for burning rather than storage
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