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Tirzepatide is not recommended for people with a family history of thyroid tumors or a family history of medullary thyroid carcinoma (MTC) and MEN2 syndrome (multiple endocrine neoplasia type 2 syndrome), as tirzepatide increases the potential risk of developing these tumors in rodents

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When administered, the peptide binds to the GHS receptors in the pituitary gland, triggering the release of GH to help reduce visible aging , enhance recovery, and increase muscle mass