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Administered as a subcutaneous weekly injection, it is a manifold single pharmacological agent that has the ability to significantly lower glucose levels, as well as improve insulin sensitivity, reduce weight and amend dyslipidemia favorably modifying the lipid profile
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We propose that the dosage and duration of GSH administration in clinical treatment be carefully evaluated and standardized to prevent overuse and mitigate the risk of chemotherapy resistance
10.1073/pnas.84.10.3434 49 DuH.MengX.YaoY.XuJ
Large-scale, multi-center studies and consortia - such as the International PCOS Network - enable the pooling of diverse patient cohorts, harmonization of diagnostic criteria, and validation of novel biomarkers across populations (37)
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