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Initially discovered in human gastric juice, it is thought to aid in the protection and healing of the stomach lining

GLP-1RAs have been shown to reduce the levels of systemic inflammatory markers.457,458 Importantly, the effective management of inflammation is widely acknowledged to play a crucial role in the prevention of cardiovascular diseases.459,460 The anti-inflammatory effects of GLP-1RAs contribute to the attenuation of atherosclerotic plaque lesion development through various mechanisms

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optional extension to 16 weeks under monitoring

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