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194 ZIP8 is crucial for T cell activation, and recent studies have highlighted its significance in T cell function and innate immunity, which may have important implications in the context of inflammatory bowel disease (IBD)

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These variants equally preserved their GSH-transferase activity, suggesting the importance of additional factors in the modulation of the negative log of GSHs acid dissociation constant (p K a ), including the ability to optimally arrange the well-described electron-sharing network which generates a positively charged electrostatic field in the G-site of GSTs 40,41

10.1152/physiol.00009.2020 102 LarsonA