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It is not approved for therapeutic use in humans, and no large-scale clinical trials have been conducted to evaluate its safety or efficacy as a medication

BPC-157 in particular has been extensively investigated in rodent gastrointestinal models, with laboratory studies examining ulcer-healing endpoints, mucosal blood flow markers, and cytoprotective signaling in gut epithelial cell preparations

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When caloric intake drops substantially, the body may experience a temporary energy deficit whilst it adapts to using stored fat for fuel

"Pentadecapeptide BPC 157 attenuates disturbances induced by neuroleptics." Neuropsychopharmacology