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Research Sources: New England Journal of Medicine: Tirzepatide as Compared with Semaglutide for the Treatment of Obesity. May 11, 2025
It differs structurally from native IGF-1 in two ways: an arginine substitution for glutamic acid at position 3 (the R3), and an additional 13-amino-acid extension at the N-terminus (the Long)
It contributes to normal red blood cell formation, supports nervous system health, and plays an important role in energy metabolism and reducing tiredness and fatigue
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