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It has been modified from the natural GLP-1 sequence to resist degradation by the enzyme DPP-4, which is why it lasts much longer in the body than natural GLP-1
Concurrently, a high degree of acylation effectively obstructs cleavage sites for RNases [67]
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When Is BPC-157 Peptide Treatment Considered
The protocol is specifically intended for use in previously stable infants in the NICU who present with acute decompensation with bradycardia and/or prolonged significant desaturation needing resuscitation, or rapidly increasing oxygen requirements, to maintain stable saturation levels, when there is no apparent explanation, e.g., technical difficulties such as an occluded or dislodged ETT and ventilator dysfunction
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