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The GIP receptor component amplifies insulin sensitivity and may enhance fat cell metabolism beyond what single-pathway agents achieve
He writes that the improvement in systolic blood pressure "was substantially larger than effects seen with CPAP therapy alone and indicate that tirzepatide may be an attractive option for those patients who seek to reduce their cardiovascular risk." Patel raised concerns about whether patients outside of a trial would stick with therapy, noting studies have shown high rates of discontinuation of GLP-1 receptor agonists
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