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To elucidate these regulation circuits and to investigate whether mTOR signaling might be involved in this abnormality, we performed gene set enrichment analysis (GSEA) on differentially expressed genes of Gclc -sufficient MZB vs

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This indicated that the functional inhibition of GJ proteins not only protects against APAP-induced hepatotoxicity but also effectively mitigates the increased sensitivity to APAP as seen in hepsin / mice

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