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To view a copy of this licence, visit About this article Cite this article Marcuzzo, M.B., Benati, M.P.D.V., Souza, D.O

Key Summary Women with PCOS often have lower glutathione (GSH) levels compared to healthy individuals Low glutathione is linked to higher oxidative stress, inflammation, insulin resistance, and ovarian dysfunction Supporting glutathione may help manage PCOS-related internal stress , not cure the condition Glutathione supports antioxidant defense, insulin sensitivity, ovarian health, and inflammation control For PCOS, glutathione works best as long-term internal support , not a whitening shortcut Discipline, sun protection, sleep, and stress control matter more than dosage Women with PCOS often experience increased oxidative stress and lower glutathione levels

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Additionally, lipotripeptides (DICAMs) inhibit and disrupt bacterial biofilms, and GPE supports neuroprotection and regeneration through ERK and PI3K/Akt signaling activation

For comparing the predictive ability of common metabolites, area under the curve (AUC), which combines the sensitivity (true positive rate) and specificity (false positive rate), was determined