R 2 = 67.18%)
Beyond weight loss, Retatrutides triple mechanism produces favorable effects on blood glucose (from GLP-1 and GIP activation), triglycerides (down 28% in trial participants at 48 weeks), blood pressure, and liver fat
Look for one that includes vitamins A, C, D, E, K, B-complex, iron, zinc, and selenium
What the new mechanism is: GLP-1 : appetite regulation, improved glucose control GIP : incretin effects that may augment metabolic benefits Glucagon receptor activity : potentially influences energy expenditure and fat metabolism (while requiring careful balancing of tolerability and metabolic effects) What results look like (so far): Phase 2 (48 weeks) published in NEJM showed substantial mean weight reductions (with higher doses showing very large effects)
If youre on the pill and considering any GLP-1 medication, speak to your GP about contraception options before you start