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To establish connection with the NO-system, L-NAME (5.0 mg/kg) (worsening) and L-arginine (200.0 mg/kg) (effective only with blunted NO-synthesis, but not alone) were given intraperitoneally alone or in combination (d-arginine 200.0 mg/kg was not effective, data not shown)

Ann Rheum Dis (2015) 74(10):1898906

ACG Clinical Guideline: the diagnosis and management of idiosyncratic drug-induced liver injury

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