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The long-term use of high doses of cyanocobalamin have also shown to leave eight times as much unusable cyanocobalamin inside the bodys cells, though the health consequences of this remain unclear (6)
This dose is typically given daily for the first week, followed by weekly injections for the first month, and then monthly maintenance doses
Muscle cramps and weakness
After this loading phase, frequency tapers to weekly injections for four to six weeks, then transitions to monthly maintenance doses
Nausea, vomiting, diarrhea, and constipation are common, especially in the early weeks of treatment
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