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Quick Answer: GLP-1 medications do not directly cause increased thirst, but some patients experience it as an indirect consequence of gastrointestinal side effects like vomiting or diarrhea that lead to dehydration
Earlier meta-analyses did report a small on-medication motor benefit, roughly one to three points, but that effect is heterogeneous and fragile: in at least one pooled analysis, it lost statistical significance once the lixisenatide trial was removed [8]
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Augmentation of the restless legs syndrome with carbidopa/levodopa