Protective effects of the GLP-1 mimetic exendin-4 in Parkinson's disease
Also, unlike therapies that are used to treat blood pressure or cholesterol, the perception that these are not chronic disease therapies may also be contributing
A meta-analysis of 5 RCTs 42,43,44,45,46 comprising 7,732 adults with T2DM did not observe any effect on cognition, as measured via mini-mental state examination (MMSE) or Montreal cognitive assessment (MoCA), of GLP-1RAs over several months compared with the baseline 38
While Ozempic and Wegovy will be fairly similar since they are both Semaglutide GLP-1, Mounjaro differs slightly in that much higher doses are required for use as a weight loss medication and is the newest on the market of these options, but comes with almost the same risks and side effects
Among 41 meta-analyses, 6 did not report primary studies