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Ortiz-RodrguezJMMartn-Cano FEFEGaitskell-PhillipsGBarrientosARodrguez-MartnezHGilMCet al

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According to the Arthritis Foundation, methotrexate stops the production of one cytokine (an inflammatory protein) and suppresses the production of others

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In the present study, DCFH fluorescence levels were consistently higher in the VPA group compared to the CT group in the cerebellum, hippocampus, posterior cortex, and striatum, indicating increased oxidative stress and supporting the effectiveness of the VPA-induced animal model

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