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4.3 Iatrogenic toxicity: ROS-induced granulosa cell death and follicle attrition Iatrogenic ovarian injury, particularly following chemotherapy with alkylating agents (e.g., cyclophosphamide, cisplatin) or anthracyclines (e.g., doxorubicin), represents an extreme form of acute oxidative insult
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Hsieh MJ, Lee CH, Chueh HY, Chang GJ, Huang HY, Lin Y, et al
The brain-access hypothesis and why it is contested One influential hypothesis for making sense of these mixed results, advanced by Christian Holscher, proposes that neuroprotective efficacy tracks a compounds ability to reach the brain
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