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no AEs Propranolol - side effects: drowsiness, sleep disturbance, weight gain, fatigue, dry mouth Side Effects of Beta-Blockers (Medical Letter Jan 2012)Fatigue, depression, bradycardia, erecticle dysfunction, decreased exercise tolerance, heart failure, worsening of peripheral aterial insufficiency, may aggravate allergic reactions, bronchospasm, may mask symptoms of and delay recovery from hypoglycemia, Ranaud's phenomenon, insomnia, vivid dreams or hallucinations, acute mental disorder, increased serum triglycerides, decreased HDL cholsterol, increased incidence of diabetes, sudden withdrawal may lead to exacerbation of antina and mycoardial infarction New Daily Persistent Headache (NDPH) Rapid development (over less than 3 days) of an unrelenting headache
Additional sensitivity analyses were conducted to check if the outcomes remained stable under other enrollment criteria, matching strategies, statistical weighting approaches, and a per-protocol approach that censored follow-up at treatment discontinuation or switching
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(Review article summarizing melanocortin agonist trials) Disclaimer: The use of PT-141 (bremelanotide) for the treatment of sexual dysfunction in men is not approved by the U.S
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