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Frontiers in Endocrinology, 5, 130

Infection risk: Though the benzyl alcohol preservative inhibits bacterial growth in the vial, any lapse in sterility (dirty needle, etc.) can introduce pathogens

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3 Nanotechnology-enabled strategies to overcome immunosuppressive barriers 3.1 Reprogramming the tumor-associated macrophage compartment Given the central role of M2-polarized TAMs in maintaining immunosuppression within the osteosarcoma TME, strategies to reprogram these cells toward a pro-inflammatory M1 phenotype have attracted considerable attention