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Weschawalit and colleagues subsequently published a randomized controlled trial in Clinical, Cosmetic and Investigational Dermatology in 2017 (N=60 women, 12 weeks) finding that oral glutathione at 250 mg/day produced favorable effects on skin elasticity, wrinkle reduction, and UV spot reduction compared with placebo

Zinc Levels: Long-term, high-dose supplementation has been linked in some studies to a potential decrease in zinc levels, suggesting that balanced formulations are best