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Li MM, Madara JC, Steger JS, Krashes MJ, Balthasar N, Campbell JN, et al
In the drugs best showing so far, the ATTAIN-1 trial, people taking orforglipron lost on average 12.4% of their baseline weight, a notch below the roughly 14% weight loss seen in similar trials of Novo Nordisks injectable Wegovy and also below the typical results seen with Eli Lillys tirzepatide, a dual GLP-1/GIP medication
It offers a level of weight loss previously achievable only through surgical interventions
The presence of similar putative fusion proteins was latter suggested in Streptococcus thermophilus, Streptococcus suis, Streptococcus sanguinis, Streptococcus mutans, Enterococcus faecalis and Enterococcus faecium [6, 25]
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