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Glutathione helps support mitochondrial health by addressing oxidative stress, which may support healthy cellular energy production
Notably, the depletion of anti-HMGB1 neutralizing antibody or arginine catabolism enzyme (AGRE) mitigates macrophage inflammatory responses, suggesting that restricting HMGB1 expression may be a potential approach for managing macrophage inflammation (103, 104)
However, despite their significant therapeutic potential in cancer treatment, it is essential to also focus on managing immune-related adverse events (irAEs)
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Bioinformatics 20 , 289290 (2004)
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